Words similar to mycrab

Example sentences for: mycrab

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Although Rab24 has been proposed as a possible regulator of autophagic processes [ 24 43 ] , the accumulation of punctate bodies in cells expressing Rab24(D123I) was not prevented by 3-methyadenine, a known inhibitor of autophagosome formation [ 44 ] . Most importantly, electron microscopy with immunogold labeling of mycRab24(D123I) in ultra-thin sections confirmed the initial impression that the inclusions are in fact localized within the nucleus.
The cytoplasmic inclusions containing mycRab24(D123I) were similar to those observed inside the nucleus, except that they were larger, with a diameter 2-3 times that of the nuclear particles (Fig.
Western blot analyses of cytosol and particulate fractions obtained from the transfected 293 cells indicated that mycRab24(wt) was present in both fractions, consistent with previous results with Rab24 and other wild-type Rab GTPases [ 25 39 ] . In contrast, mycRab24(D123I) was found exclusively in the particulate fraction (Fig.
However, in some cells with larger and more numerous inclusions we observed discontinuities in the anti-lamin staining of the nuclear envelope and some co-localization of lamin with mycRab24(D123I) in the intranuclear aggregates.
The latter point is clearly illustrated by the overlap of GR-GFP (green) fluorescence with rhodamine-IgG staining for mycRab24(D123I) (red) in Fig.