Words similar to multifunctional
Example sentences for: multifunctional
How can you use “multifunctional” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is important not only for understanding nature, but also for technological applications, including the fabrication of large-scale integrated nanocircuits using a bottom-up approach, and the preparation of multifunctional “smart” nanomaterials.
For instance, the conservation of gene order in metabolic-related runs is often related to their coding for enzymes that act sequentially in a pathway, forming multifunctional complexes in several cases.
Another serious complication in structure-based deduction of function is the intrinsic limit on our ability to compare distantly related sequences and to recognize the role of specific residue subsets in multifunctional proteins.
Indeed, both human homologs of yPOP2, hCAF1 and hPOP2, lack the 148 N-terminal amino acids which are, in yPOP2, required for transcriptional activation, whereas the yPOP2 C-terminus, which is involved in the interaction with yCCR4, is conserved in hCAF1 [ 11 ] and hPOP2 [ 19 ] . Similarly, hNOT2, the human homolog of the yNOT2 component of the CCR4-NOT complex, harbors a N-terminal domain divergent from that of yNOT2 -required for transcriptional activation and interaction with the yeast ADA2 factor-, but has conserved the C-terminal domain which is absolutely required for the yCCR4-associated function of yNOT2 [ 19 20 ] . Therefore, it looks as if genes of the CCR4-NOT complex have undergone a "concerted" phylogenetic evolution, with the yeast genes encoding multifunctional proteins and the animal genes only encoding "specialized" proteins specific for the CCR4-NOT complex.
Second, the N- and C-terminal domains observed in the yCCR4 multifunctional protein might have been split into two -or more- independent proteins in animals.
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