Example sentences for: multicenter

How can you use “multicenter” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Despite its decline as a result of widespread antiretroviral therapy and chemoprophylaxis, PCP has remained a common complication in patients with HIV infection [ 2 3 ] . In a prospective multicenter study of HIV seropositive patients, for 79% of those with a CD4 +lymphocyte count < 200/μL receiving PCP chemoprophylaxis, the rate of first episode PCP was 3.3 per 100 person-years [ 4 ] . Although actual data were not available, high rates of noncompliance with and lack of access to antiretroviral therapy and chemoprophylaxis were likely in our study population, which included a significant number of medically underserved patients without perceived risk for HIV.

  • The classic chest radiographic findings of patients with PCP include bilateral diffuse opacities [ 7 ] . However, some patients present with unusual chest radiographic findings [ 7 8 ] . In a multicenter study from the United States, the in-hospital mortality rate of hospitalized patients with cytologically confirmed PCP was 14% [ 9 ] . The PIP study showed that PCP is unusual in patients with normal CD4 +lymphocyte count and serum LDH concentration, can present with atypical chest radiographic findings, can be diagnosed from induced sputum in most of the cases, and is associated with 11% mortality.

  • One way of dealing with the logistic challenges inherent in genetic studies is to collect cases from an isolated population, such as Iceland [ 79 ] . However this approach requires an integrated health care database not easily applicable within the US health care model, and the required community consent is probably not possible within the US legal/ethical framework [ 80 81 ] . Logistic difficulties have been mitigated by the steady evolution in multicentered clinical trials that has occurred in the field of stroke research [ 82 ] . SWISS is designed as a multicenter clinical trial, and the use of a nationwide home health agency for phlebotomy service enables us to obtain blood from siblings living far away from one another.

  • The Siblings With Ischemic Stroke Study (SWISS) is a multicenter affected sibling pair study with the aim of identifying chromosomal regions linked to ischemic stroke by using genome-wide scanning.

  • Trough levels of TAC and SRL were not available as they were processed in central core laboratory as a part of multicenter study.


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