Words similar to multicenter
Example sentences for: multicenter
How can you use “multicenter” in a sentence? Here are some example sentences to help you improve your vocabulary:
We therefore performed standardized pulmonary function testing (PFT) on HTLV-I and HTLV-II infected persons participating in the HTLV Outcomes Study (HOST), a prospective multicenter cohort study of the health outcomes of HTLV infection that was initiated as part of the National Heart Lung and Blood Institute Retrovirus Epidemiology Donor Study.
Patient samples were derived from 2 randomized, open-label, multicenter Phase III clinical trials comparing standard of care chemotherapy alone or combined with SU5416 in patients with metastatic colorectal cancer.
Despite its decline as a result of widespread antiretroviral therapy and chemoprophylaxis, PCP has remained a common complication in patients with HIV infection [ 2 3 ] . In a prospective multicenter study of HIV seropositive patients, for 79% of those with a CD4 +lymphocyte count < 200/μL receiving PCP chemoprophylaxis, the rate of first episode PCP was 3.3 per 100 person-years [ 4 ] . Although actual data were not available, high rates of noncompliance with and lack of access to antiretroviral therapy and chemoprophylaxis were likely in our study population, which included a significant number of medically underserved patients without perceived risk for HIV.
Similar larger prospective multicenter studies are recommended.
Subjects in the initial investigation were participants in an open-label, multicenter, international Phase III study in which patients were randomized to be treated with either the standard-of-care 5-FU/LV chemotherapy (control arm) regimen alone or 5-FU/LV chemotherapy co-administered with SU5416 (treatment arm) administered twice weekly via intravenous infusion at a dose of 145 mg/m 2(for more detail see [ 13 14 ] ). Affymetrix expression profiling technology was applied to RNA from matched peripheral blood mononuclear cell (PBMC) sample pairs (before and after treatment) harvested from subjects, for assessment of changes in gene expression that might correlate with SU5416 administration.
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