Words similar to multi-protein
Example sentences for: multi-protein
How can you use “multi-protein” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, the sequences of the five nAChR monomers (alpha3, alpha4, alpha7, beta2 and beta4) were aligned to AChBP in a multi-protein sequence alignment.
We and others and we have reported that μ- and δ-opioid receptors become tyrosine phosphorylated after agonist-stimulation [ 11 12 ] . Tyrosine phosphorylation of a membrane-bound protein is an essential step in ERK activation, because it creates SH2-binding domains that allow Shc and other proteins to associate into a multi-protein signalling complex.
Thus to understand the function of multi-protein complexes, or whole proteomes, from a structural viewpoint, it is necessary to have a model for many proteins encoded by the genome of an organism.
For the GPCR model, the tyrosine kinase(s) involved and the site of this multi-protein complex formation is less clear.
The DLG5 gene encodes for a protein that is a member of the MAGUK (Membrane Associated Guan late Kinase homologs) family of proteins located in the plasma membrane [ 2 ] . MAGUK is a new family of proteins that act as a molecular scaffold for intracellular signaling pathways [ 11 ] . The MAGUK family of proteins is characterized by domains that interact with other proteins to create an assembly of large multi-protein complexes [ 10 ] . The PDZ (PSD-95, DLG and ZO-1) domains are the best characterized for their binding to the C-terminal region of channels and transmembrane proteins [ 11 ] . Usually each protein has 1-3 copies of such domains [ 8 12 13 ] . The SH3 domain (Src homology 3) are present in proteins that couple transmembrane receptors to signaling molecules [ 14 ] . The presence of this domain in MAGUKs increases their possibilities of interacting with signaling pathways.
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