Words similar to mtor

Example sentences for: mtor

How can you use “mtor” in a sentence? Here are some example sentences to help you improve your vocabulary:

Although the molecular signaling mechanisms that transduce the effects of phasic patterns of work activity to modify muscle mass are incompletely understood, recent evidence implicates pathways that include the signaling molecules PI3 kinase, Akt, mTOR, S6K, and ERK, the ubiquitin ligases MAFbx and MuRF1, and transcription factors of the FOX superfamily in the control of both catabolic and anabolic processes [21,22,23,24].
Inhibition of mTOR increases life span in
One such candidate is the rapamycin analog CCI779, which has been suggested to inhibit the AKT signaling pathway, probably through inhibition of mTOR (target of rapamycin), a potential target of AKT [reviewed in ref.
Clinical trials using the rapamycin analog CCI-779 show promise for this strategy [ 22 ] . Rapamycin and its synthetic analogs block mTOR kinase activity leading to dephosphorylation of 4EBP and other mTOR substrates.
However, it is likely that carbohydrate and protein may differentially alter nutrient-sensing pathways such as Sir2 and mammalian target of rapomyocin (mTOR), which are gaining acceptance as mediators of the life-span extension effects of CR [16].