Words similar to mtor

Example sentences for: mtor

How can you use “mtor” in a sentence? Here are some example sentences to help you improve your vocabulary:

Rapamycin inhibits activation of p70 S6 kinase, a downstream effector in the PI 3-kinase signaling pathway [ 13 ] . Rapamycin forms a complex with FK506-binding protein 12 and this complex blocks the kinase activity of mTOR (mammalian target of rapamycin), a kinase upstream of p70 S6 kinase [ 20 ] . The IC 50 for p70 S6 kinase inhibition by rapamycin is ~0.
Inhibition of mTOR increases life span in
Clinical trials using the rapamycin analog CCI-779 show promise for this strategy [ 22 ] . Rapamycin and its synthetic analogs block mTOR kinase activity leading to dephosphorylation of 4EBP and other mTOR substrates.
Rapamycin and its analogs are potent inhibitors of mTOR and lead to cell cycle arrest.
Thus expression of the mutant mimics the effects of rapamycin on 4EBP but does not affect the other targets of mTOR.