Words similar to mtdna

Example sentences for: mtdna

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Schapira has devised a classification scheme for mitochondrial defects [ 8] based primarily on whether or not the affected gene product is directly involved in oxidative phosphorylation and whether it is encoded by mtDNA or nuclear DNA.
In animals, inclusion of mtDNA evidence in biogeographic and systematic analyses often reveals unexpected diversity or discordance with morphology, which then prompts re-evaluation of morphological and ecological characteristics and, if warranted, taxonomic revision.
There is also the need to examine groups with frequent (possibly cryptic) hybridization, recent radiations, and high rates of gene transfer from mtDNA to the nucleus.
More specifically, using some level of mtDNA divergence as a yardstick for species boundaries ignores the low precision with which coalescence of mtDNA predicts phylogenetic divergence at nuclear genes (Hudson and Turelli 2003).
Neuromuscular disorders were the first to be studied, and direct evidence of mitochondrial DNA (mtDNA) abnormalities was demonstrated in 1988 [ 1 2 ] . However, only 6% of the patients suspected of having mitochondrial disorders have been found to have mtDNA point mutations or deletions [ 3 ] . Most pediatric mitochondrial disorders are caused by defects in nuclear genes and with an autosomal recessive inheritance [ 4 ] . This case of neonatal mitochondrial dysfunction presenting with hyperammonemia and ventricular tachycardia expands the clinical spectrum of these disorders.