Example sentences for: mrnas

How can you use “mrnas” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both mutant mRNAs encode internally deleted proteins without a frameshift.

  • It has been proposed that loss of hERα expression in breast tumors is the result of aberrant RNA processing [ 40 41 42 43 ] . These aberrantly spliced mRNAs, if translated, could lead to truncated receptors with hormone binding but not DNA binding function [ 44 ] . Further, there is evidence for the role of RNA processing in oncogenesis [ 45 46 ] . Many studies, including those on human hnRNP A2/B1 and the CD44 gene, suggest that high fidelity pre-mRNA splicing is critical to normal cellular function and may play a key role in oncogenesis and breast cancer progression [ 47 48 ] . The strong association between nmt55/p54 nrband hERα expression indicates that nmt55/p54 nrbmay be an important marker for breast cancer progression.

  • Nematodes process many mRNAs by trans -splicing to SL1 and other splice leader sequences [ 57 58 ] and in C. elegans use of different splice leaders is tied to genome organization in operons [ 59 ] . SL1 is the predominant nematode splice leader and is highly conserved across many species.

  • Constructs for generating the control reagents are available through the American Type Culture Collection (ATCC); accession numbers are given in Table 1. We describe how scaled frequency normalization can be used to estimate message abundance in cRNA, compute a chip sensitivity metric and provide a natural scale for damping spurious signals from below-sensitivity mRNAs.

  • Frequencies of CD4 +memory T cells expressing cytokine and activation marker mRNA in RA synovium are shown in Table 1. IL-2, IL-4, and IL-6 were not expressed by the synovial tissue CD4 +CD45RO +T cells, whereas 2-20% of cells expressed the other cytokine mRNAs.


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