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Example sentences for: mrnas

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Interactions between spectrin and actin filaments are stabilized by protein 4.1 and regulated by a variety of accessory proteins [ 17 ] . Protein 4.1 also may connect the protein translation apparatus to the cytoskeleton through interactions with a component of the eukaryotic translation initiation factor-3 complex, eIF3-p44 [ 18 ] . Interestingly, mRNAs for multiple proteins involved in translation, such as various ribosomal proteins, were enriched in the cytoskeleton fraction (Table I).
Several of these genes are known to encode immediate early transcription factors (for example, FosB, NAB2, ATF-3, NOT1) that are induced by a wide range of cellular stimuli, and this class of transcription factors is well known to have unstable mRNAs [ 32].
The CV of the mean expression level is below 7% for any set of mRNAs larger than roughly 10% of the total.
Among the mRNAs known to be edited in Drosophila are those encoded by cacophony (a calcium channel gene) [ 27], paralytic (a sodium channel gene) [ 28] and GluCla (a chloride channel gene) [ 29], all of which have multiple editing sites in their coding sequences.
Other inducible transcription factors with labile mRNAs have more lymphocyte-specific functions, such as IRF-4, a factor that is required for lymphocyte activation but is not required in other lineages [ 33].