Example sentences for: mpt-mo
How can you use “mpt-mo” in a sentence? Here are some example sentences to help you improve your vocabulary:
MoeZ is one of several MSAE-like conceptually translated protein sequences identified by the M. tuberculosis genome sequencing group at Sanger Center [ 14 ] . Although coding for a putative protein with high sequence similarity to MoeB, moe Z was so named because it had no genetic linkage to other MPT-Mo synthesis genes.
Since MPT-Mo is required for nitrate reductase activity [ 12 ] , the activity of this enzyme can be used as a diagnostic indicator for the presence of the MPT-Mo synthetic pathway [ 7 ] .
Two moeB sequences with evidence for function include a knockout of the open reading frame encoding GenBank accession number BAA35521, which was shown to cause the accumulation of precursor Z in E. coli [ 13 ] and accession number Z95150, which was found to be located within a cluster of other MPT-Mo synthesis genes of Mycobacterium tuberculosis [ 14 ] . MSAEs from eukaryotic organisms have also been characterized: MOCS3 (GenBank accession number NM_014484) from humans and cnx 5 from Arabidopsis thaliana [ 15 ] , respectively, have been sequenced, and cnxF from Aspergillus nidulans [ 16 ] has been both sequenced and physiologically characterized.
However, since CTN1, a mutant of P. stutzeri , missing a 171 kb genomic fragment that includes moeZ [ 17 ] , reduces nitrate as does the wild-type (data not shown), it is evident that Ps-moeZ is not necessary for MPT-Mo synthesis.
Perhaps MoeZ fulfills MSAE function as part of a modified MPT-Mo pathway in these species.
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