Words similar to mpf

Example sentences for: mpf

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In addition to MPF, mitogen-activated protein (MAP) kinase is also known as an important protein kinase that regulates the meiotic cell cycle [ 35].
0 μg/mlMG-132 may be related to the sustained elevation of MPF activity noted in rat oocytes exposed to MG-132 [ 42 ] and the stabilization of polyubiquitinated proteins and enhanced deubiquitination of nucleosomal histones in chromatin following proteasomal inhibition [ 62 ] .
Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .
However, MAP kinase and MPF activities do not vary between M I and M II of porcine oocytes because phosphorylations of MAP kinase and histone H1 kinase which corresponds to MPF activity reach the peak level at M I and remain high beyond M II [ 37, 38].
The first is the transfer of nuclei in G1, S or G2 phase into the preactivated recipients after reducing MPF activity and the second is the transfer of nuclei in GO or G1 phase directly into M II oocytes having high MPF activity [ 12].