Example sentences for: mpf
How can you use “mpf” in a sentence? Here are some example sentences to help you improve your vocabulary:
In mouse oocytes, MAP kinase plays a more important role in controlling chromatin and microtubule behavior than MPF [ 36].
Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .
In the M II oocyte, the membrane of the donor nucleus is broken down and the chromosomes are prematurely condensed due to the high activity of MPF.
The secreted form has been referred to as megakaryocyte potentiating factor (MPF) for its ability to stimulate the megakaryocyte colony forming activity of murine IL-3 in mouse bone marrow cell culture [ 23 24 ] . Mesothelin expression is induced in a variety of cancers including ovarian, pancreatic, lung, and cervical cancer [ 25 26 ] . The soluble portion of mesothelin has drawn attention as a potential serum tumor marker since it is highly over-expressed in patients with ovarian carcinomas and pancreatic adenocarcinomas [ 27 28 ] .
When donor nuclei are transferred into non-treated M II recipient oocytes that have high MPF activity, various changes referred to as nuclear remodeling occur in the introduced nuclei.
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