Example sentences for: mpf
How can you use “mpf” in a sentence? Here are some example sentences to help you improve your vocabulary:
When donor nuclei are transferred into non-treated M II recipient oocytes that have high MPF activity, various changes referred to as nuclear remodeling occur in the introduced nuclei.
Because many studies suggest that exposure to high activity of MPF is effective for reprogramming a donor nucleus from a differentiated cell [ 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 14], M I oocytes may reprogram somatic cell nuclei as well.
In mouse oocytes, MAP kinase plays a more important role in controlling chromatin and microtubule behavior than MPF [ 36].
0 μg/mlMG-132 may be related to the sustained elevation of MPF activity noted in rat oocytes exposed to MG-132 [ 42 ] and the stabilization of polyubiquitinated proteins and enhanced deubiquitination of nucleosomal histones in chromatin following proteasomal inhibition [ 62 ] .
Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .