Example sentences for: mpf

How can you use “mpf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • When donor nuclei are transferred into non-treated M II recipient oocytes that have high MPF activity, various changes referred to as nuclear remodeling occur in the introduced nuclei.

  • Because many studies suggest that exposure to high activity of MPF is effective for reprogramming a donor nucleus from a differentiated cell [ 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 14], M I oocytes may reprogram somatic cell nuclei as well.

  • In mouse oocytes, MAP kinase plays a more important role in controlling chromatin and microtubule behavior than MPF [ 36].

  • 0 μg/mlMG-132 may be related to the sustained elevation of MPF activity noted in rat oocytes exposed to MG-132 [ 42 ] and the stabilization of polyubiquitinated proteins and enhanced deubiquitination of nucleosomal histones in chromatin following proteasomal inhibition [ 62 ] .

  • Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .


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