Words similar to mp-release
Example sentences for: mp-release
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The essential step in plasma membrane destabilization and MP-release very likely is a caspase-dependent sphingomyelin hydrolysis, which leads to the production of ceramide [ 28 29 30 ] . It is possible, however, that sphingomyelin hydrolysis and MP-release may be a consequence of the action of initiator caspases or other ZVAD sensitive proteases rather than only executioner caspases [ 15 31 32 ] . Our study was performed in HUVEC culture, which may have particular properties in respect of MP release when compared with endothelial cells from other organs.
Plasma membrane blebbing and MP-release are generally accepted as typical signs of cell apoptosis [ 17 ] .
Since MP-release from endothelial cells after proapoptotic stimulation was not studied before, we focused on its characterization.
Similar short-time activation of HUVEC with phorbol myristate acetate (PMA) (1 μg/mL), human thrombin receptor activating peptide (TRAP) 1-50 μmol/L, human thrombin (THR) 0.1-10 NIH Unit/mL, human tissue plasminogen activator (TPA) 3.5 kU/mL or human angiotensin II (AGTII) 1 μmol/L did not cause any significant increase in MP-release (Fig.
MP-release did not correlate with the level of cell apoptosis in HUVEC stimulated with camptothecin