Example sentences for: mp-release

How can you use “mp-release” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Interestingly, a ten times lower concentration of CPT (500 nM) also induced significant MP-release after only 4 hrs of treatment (Fig.

  • It is difficult to understand why 500 nM CPT caused higher MP-release than 5 μM CPT in subconfluent HUVEC.

  • The essential step in plasma membrane destabilization and MP-release very likely is a caspase-dependent sphingomyelin hydrolysis, which leads to the production of ceramide [ 28 29 30 ] . It is possible, however, that sphingomyelin hydrolysis and MP-release may be a consequence of the action of initiator caspases or other ZVAD sensitive proteases rather than only executioner caspases [ 15 31 32 ] . Our study was performed in HUVEC culture, which may have particular properties in respect of MP release when compared with endothelial cells from other organs.

  • To investigate whether maturation of the cell culture influences the degree of MP-release from HUVEC in response to CPT, we compared MP-release from subconfluent HUVEC (50% of confluence) at 24 hrs in culture, HUVEC reaching confluence at 48 hrs in culture and overgrown HUVEC at 72 hrs in culture.

  • We further focused our study on MP-release from HUVEC after proapoptotic stimulation with the topoisomerase I inhibitor camptothecin (CPT).


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