Example sentences for: morphine

How can you use “morphine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus the present study was designed, (1) to describe the activation profiles of a set of opioid ligands not previously defined at an isolated cell system expressing only δ opioid receptors, and (2) to compare the relative efficacies and potencies of these ligands to the strongest ligand in the set, metazocine, to the common opioid analgesic, morphine and to the endogenous δ opioid ligand, met-enkephalin.

  • The other ligands, met-enkephalin, WIN 44,441, hydromorphone and Butorphanol, exhibited potencies of 10-100 nM; metazocine and SKF 10047, 100-200 nM, and nalbuphine, dezocine and morphine, 400-1000 nM.

  • This shows that using a high-affinity agonist such as morphine, it is not possible to trigger the endocytosis process.

  • Thus, fentanyl, but not morphine, can elicit physiological changes that are mediated by activation of δ opioid receptors.

  • The authors suggest that morphine has low intrinsic activity at μ-opioid receptor compared for instance to the lower affinity μ agonist [D-Ala 2,N-MePhe 4,Gly 5-ol]enkephaline (DAMGO) which is able to trigger an internalization process.


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