Example sentences for: monotonic

How can you use “monotonic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Initial simulation estimates based on monotonic population expansion suggested that useful LD was unlikely to extend beyond 3 kb, implying a number of 500,000 SNPs necessary for a whole-genome scan [ 32 ] . Another study looking at real data found that LD extended over much larger distances and arrived at an estimate as small as 30,000 SNPs, or 1 SNP per 100 kb [ 33 ] . Recent evidence suggests that the genome consists of blocks of high LD (haplotype blocks) separated by recombination hot spots [ 34 ] . Within each block, a limited number of common haplotypes (three to five) typically capture about 90% of all chromosomes, which means that a reduced number of SNPs would be needed to characterize these haplotypes [ 35 ] . Thus, the recently initiated construction of a haplotype map of the human genome may facilitate selection of SNP markers for genomewide association studies like ours.

  • We again see a monotonic behavior of the other variables across quartiles.

  • A monotonic series is one whose every term is greater than (less than) or equal to the previous term.

  • Spearman's rank order correlation determined significant monotonic relationships that illuminate important connections between structural features in tissue elements and genes that have been reported as significantly up- or downregulated by CCl 4 treatment in previous studies [ 7 ] . Principal component analysis (PCA), as described in Materials and methods, was carried out to reduce the complexity of the data [ 15 ] and then to relate individual animals to specific phenotypic groups.

  • A U-shaped curvilinear relationship between sleep duration and BMI was observed for women, but for men, there was a monotonic trend towards higher BMI with shorter sleep duration.


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