Example sentences for: mmp-

How can you use “mmp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • There were low basal expressions of MMP-1, MMP-13, and Bcl-3, which were increased in the presence of IL-1 and inhibited by CDDO, following the trends observed in SW-1353 and human primary chondrocytes (data not shown).

  • In a previous study, Northern blot analysis showed that treating SW-1353 cells with 300 nM CDDO for 24 hours before treatment with IL-1 inhibited the expression of MMP-1 and MMP-13 [ 23 ] . In the present study we used quantitative real-time RT-PCR to examine the action of CDDO on the expression of MMP-1 and MMP-13 in SW-1353 cells and in two primary cultures: human primary chondrocytes and OA synovial fibroblasts.

  • Most studies have concentrated on the contribution of MMP-9 to the synovitis, because synovial fluid and serum MMP-9 levels are markedly increased in inflammatory arthropathies.

  • To determine whether the expression and activity levels of MMP-2 and MMP-9, and their regulators MMP-14 and tissue inhibitor of metalloproteinase (TIMP), are associated with early erosion formation in patients with synovitis of recent onset.

  • We have shown in a quantitative manner that in all three cell types, MMP-1 and MMP-13 are inducible with IL-1, and that CDDO inhibits the expression of these collagenases, with optimal inhibition being observed after 24 hours of pretreatment with CDDO.


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