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Example sentences for: mlst

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For over a decade the idea of representing biological sequences in a continuous coordinate space has maintained its appeal but not been fully realized [ 1 2 3 ] . The basic idea is that sequences of symbols, such as nucleotides in genomes, aminoacids in proteomes, repeated sequences in MLST [Multi Locus Sequence Typing, 4], words in languages or letters in words, would define trajectories in this continuous space conserving the statistical properties of the original sequences [ 3 5 6 7 8 9 ] . Accordingly, the coordinate position of each unit would uniquely encode for both its identity and its context, i.e. the identity of its neighbors [ 10 ] . Ideally, the position should be scale-independent, such that the extraction of the encompassing sequence can be performed with any resolution, leading to an oligomer of arbitrary length.
However, not all biological sequences are composed of units that are functionally equally distinct from each other, as is the case of proteomic data and Multi-locus sequence typing [MLST, 4].