Example sentences for: missegregation

How can you use “missegregation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Irregular partitioning of chromosomes during the second meiotic division has also been reported in fission yeast rec7 mutants [ 10 ] , so MII missegregation may be a relatively common fate for chromosomes in hyporecombination mutants.

  • Although they exhibit a striking difference in their apparent MI nondisjunction frequencies, the rec12-D15 (null) and rec12-Y98F (active site) mutants manifest at most a two-fold difference in the absolute frequency of meiotic diploids exhibiting MII missegregation patterns (Figures 4, 5, Table 2).

  • it has been shown that driving transcription through a centromere via an inducible promoter prevents cohesin from associating and results in chromosome missegregation and cell death [13].

  • Catalytically-inactive Rec12-Y98F protein apparently cannot enhance the fidelity appropriate MII segregation, relative to MII missegregation levels in cells lacking Rec12 entirely.

  • However, about half of the diploids from rec12-117 and rec12-D15 meioses, and 14% of diploids from rec12-Y98F meioses, exhibited mixed patterns of MI or MII missegregation for different chromosomes within individual cells (Table 2).


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