Words similar to misregulation

Example sentences for: misregulation

How can you use “misregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

We have shown that disruption of a single splice donor site within a multi-exon locus can lead to a dramatic misregulation of RNA splicing.
The combination of microarray data and cluster analysis to make a genetic portrait of a disease has been used to characterize breast tumors [ 9], to categorize the subtype of diffuse large B-cell lymphoma [ 10], and to identify genes whose expression is associated with mitotic misregulation and human aging [ 11].
We found a similar phenotype upon overexpression of Hoxd-4 in our transgenic system (Kappen, manuscript in preparation), whereas overexpression of the LIM-homeodomain transcription factor Isl-1 did not cause abnormalities in cartilage but other developmental defects [ 1 9 ] . The observation that cartilage is affected by misregulation of Hoxc-8 and Hoxd-4, but not by a divergent homeobox gene, indicates that the capacity to regulate cartilage differentiation is specific to homeobox genes of the Hox subclass.
Disruption of ifkAresults in misregulation of countin
This methodology [ 8] has been used by others to define the gene-expression profile of breast tumors [ 9], to subtype diffuse large B-cell lymphomas [ 10] and to identify genes whose expression is associated with mitotic misregulation and human aging [ 11].