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Example sentences for: mii

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Oocytes were collected and processed according to a mass-harvest procedure [ 63 ] and chromosomes were C-banded [ 64 ] to distinguish between complete dyads (MII chromosomes) and disjoined dyads (single chromatids).
Oocytes residing in MII for longer periods of time tend to display higher frequencies of PCS; whereas, those deferred in MI spend less time in MII prior to fixation.
It has been suggested previously [ 38 ] that these phenotypes are characteristic of a defect in meiosis II because spore formation in S. pombe is controlled by the spindle pole body of the MII spindle [ 40 41 42 ] .
PCS of homologous chromosomes and sister chromatids prior to establishing proper kinetochore-spindle attachment during meiosis I increases the probabilities of both homologues going to the same pole and of equational division of sister chromatids during anaphase I. Upon normal fertilization, MII oocytes with an additional chromosome result in trisomic zygotes; whereas oocytes containing an extra chromatid would be expected to produce 50% trisomic zygotes due to random segregation during anaphase II.
However, only about 50% of diploid meiotic products from rec12-D15 (null) mutant meioses were heterozygous for centromere linked markers (Figure 5E), indicating that some fraction of the products were derived from precocious separation of sister chromatids (PSS) and/or MII nondisjunction (Figure 5C, 5D).