Words similar to mii
Example sentences for: mii
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However, about half of the diploids from rec12-117 and rec12-D15 meioses, and 14% of diploids from rec12-Y98F meioses, exhibited mixed patterns of MI or MII missegregation for different chromosomes within individual cells (Table 2).
We therefore propose that Rec12 protein mediates a signal, strictly dependent upon its active site tyrosine, that is required for the equational division of MII.
Although the frequency of homologue separation increased with MG-132 dose, the sample size of 11 oocytes is much too low to comment about their possible origin or their influence on other abnormalities detected in MII oocytes.
In addition, we report that Rec12 and its active site tyrosine are required for proper equational chromosome segregation during MII.
The origin of single, unpaired chromatids in MII oocytes has been proposed to result from premature separation of sister chromatids prior to anaphase I [ 56 57 ] . The possibility exists that both SC and aneuploidy may have originated from PCS of homologues and sister chromatids during the MAT of meiosis I. Upon removal of MG-132 from the culture media during meiosis I and the subsequent resumption of OM and proteasomal activity, faulty kinetochore-microtubule attachment accompanied by degradation of cohesion proteins could conceivably lead to PCS of homologues and sister chromatids.
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