Words similar to mifepristone

Example sentences for: mifepristone

How can you use “mifepristone” in a sentence? Here are some example sentences to help you improve your vocabulary:

RU486 (Mifepristone) has shown remarkable antiglucocorticoid and antiprogestrone activities both in vitro and in vivo [ 1 2 ] . This compound has a high affinity for ligand binding sites of both receptors [ 1 2 ] . Current clinical uses of RU486 are limited to its function as a progestrone antagonist [ 1 2 ] , where it was approved in France in 1988, and recently in the USA as a means to induce early termination of pregnancy [ 1 2 3 ] .
Nevertheless, pharmacological antagonism of glucocorticoid (type II) receptor by mifepristone (RU486) was reported to reverse high fat diet-induced obesity [ 14 ] . Since diet-induced obesity does not entail elevated glucocorticoid levels [ 15 16 17 ] , this result suggests that reduction of glucocorticoid levels would reverse obesity even when glucocorticoid levels are not elevated.