Words similar to midline
Example sentences for: midline
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5) when the midline defects are first detectable in both Shh -/-and Smo -/-embryos, but prior to any general retardation of growth and development [ 26 27 ] . In both Shh +/-and Smo +/- Ptc1 lacZ /+embryos, Ptc1 was detected in ventral neural tube, somites and lateral plate mesoderm (Figure 3e,i,m).
A role for BMP-5 in dorsal forebrain patterning has been proposed based on its expression in the dorsal midline of the developing forebrain and observations that ectopic expression of BMP-5 in the developing neural tube of chicks markedly downregulates ventral markers while maintaining dorsal markers [ 5 7 ] . Further support for BMP-5 regulation of early forebrain development has been provided by studies of Bmp5/Bmp7 double mutants [ 6 ] . However, reports that BMP-5 in the mouse brain exhibits peak expression levels in the adult striatum and brainstem and that maximal expression in the hippocampus and cerebellum occurs at E18 through PN1 and again in the mature nervous system [ 3 ] , suggest additional roles for BMP-5 during later stages of neural development and into adulthood.
As previously reported [ 33], neurites extending on the corpus callosum near the midline and medial to the cingulum were mostly limited to orientations that were in parallel with the longitudinal axis of the fiber tract.
1B,1C), and in the midline (Fig.
They are congregated preferentially near the midline.
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