Words similar to micrornas

Example sentences for: micrornas

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Similar to siRNAs, the natural small RNAs, dubbed microRNAs (miRNAs), arise from Dicer processing of dsRNA precursors and are incorporated into RISC (Denli and Hannon 2003).
This view of the evolutionary history of RDRPs is compatible with the presence of RDRP homologs in phages and with their role in replicating microRNAs (potential relics of the RNA world) during PTGS in eukaryotes.
Our collective ignorance of the totality of non-coding RNA genes was laid bare by recent work on microRNAs (miRNAs), an abundant family of 21-22 nucleotide non-coding RNAs [ 2 3 ] . The founding members of this family, lin-4 and let-7, were identified through forward analysis of extant Caenorhabditis elegans mutants [ 4 5 ] . Both of these RNAs are post-transcriptional regulators of developmental timing that function by binding to the 3' untranslated regions (3' UTRs) of target genes [ 5 6 7 8 ] . Although they were long regarded as genetic curiosities possibly specific to nematodes, let-7 was subsequently found to be broadly conserved across bilaterian evolution [ 9 ] and miRNA genes are now recognized as a pervasive and widespread feature of animal and plant genomes [ 10 11 12 13 14 15 16 ] .
All 23 of the known microRNAs in Drosophila are located precisely in the Release 3 genome.
MicroRNAs were aligned by BLASTN analysis; a single exact match was found for each of the microRNAs listed in FlyBase.