Words similar to mib-arrested

Example sentences for: mib-arrested

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The transient character of these responses may explain the failure to cause efficient S phase entry in the presence of MIB, in particular as co-expression of cyclins was previously shown to synergize with SKP2 in stimulating CDK2 activity and S phase entry [ 30 31 ] . In addition, cyclin A is frequently overexpressed in prostate cancers [ 51 ] . In future experiments, it will be interesting to determine the effect of combined overexpression of SKP2 and cyclin A and cyclin E on cell cycle progression of MIB-arrested cells.
In summary, SKP2 overexpression caused transient upregulation of cyclin A expression and CDK2 activity, but was inefficient in promoting S phase entry of MIB-arrested LNCaP cells.
Although, in three independent experiments, the fraction of cells in S phase was significantly (p = 0.009) higher in MIB-arrested cells overexpressing SKP2 (7.