Words similar to met-enkephalin
Example sentences for: met-enkephalin
How can you use “met-enkephalin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The rank order of efficacy of the ligands tested was metazocine = xorphanol ≥ fentanyl = SKF 10047 = etorphine = hydromorphone = butorphanol = lofentanil > WIN 44,441 = Nalbuphine = cyclazocine ≥ met-enkephalin >> morphine = dezocine.
A previous study showed that kelatorphan in addition to blocking the degradation of the exogenous peptide by suppressing the aminopeptidase activity, markedly increased the spontaneous release of endogenous Met-enkephalin in vivo and in vitro ( 16).
Comparison of the efficacies of the set of agonists in this study to that of the endogenous ligand, met-enkephalin, showed that all were full agonists.
The other ligands, met-enkephalin, WIN 44,441, hydromorphone and Butorphanol, exhibited potencies of 10-100 nM; metazocine and SKF 10047, 100-200 nM, and nalbuphine, dezocine and morphine, 400-1000 nM.
Statistical analysis showed that most of the agonists tested had efficacies that were not significantly different from that of the endogenous ligand met-enkephalin.