Words similar to met-enkephalin
Example sentences for: met-enkephalin
How can you use “met-enkephalin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The rank order of efficacy of the ligands tested was metazocine = xorphanol ≥ fentanyl = SKF 10047 = etorphine = hydromorphone = butorphanol = lofentanil > WIN 44,441 = Nalbuphine = cyclazocine ≥ met-enkephalin >> morphine = dezocine.
Such a moderate affinity makes it possible for nalorphine to antagonize the effect of other ligands or the endogenous ligand (like met-enkephalin) at δ opioid receptors while possibly acting as an agonist at other opioid receptors.
Statistical analysis showed that most of the agonists tested had efficacies that were not significantly different from that of the endogenous ligand met-enkephalin.
Thus the present study was designed, (1) to describe the activation profiles of a set of opioid ligands not previously defined at an isolated cell system expressing only δ opioid receptors, and (2) to compare the relative efficacies and potencies of these ligands to the strongest ligand in the set, metazocine, to the common opioid analgesic, morphine and to the endogenous δ opioid ligand, met-enkephalin.
Moreover, fentanyl, metazocine and xorphanol could be considered "super agonists" at delta receptors based on having efficacies significantly greater than met-enkephalin.
Loading...