Words similar to met-enkephalin
Example sentences for: met-enkephalin
How can you use “met-enkephalin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The other ligands, met-enkephalin, WIN 44,441, hydromorphone and Butorphanol, exhibited potencies of 10-100 nM; metazocine and SKF 10047, 100-200 nM, and nalbuphine, dezocine and morphine, 400-1000 nM.
A previous study showed that kelatorphan in addition to blocking the degradation of the exogenous peptide by suppressing the aminopeptidase activity, markedly increased the spontaneous release of endogenous Met-enkephalin in vivo and in vitro ( 16).
The rank order of potency of these ligands was; etorphine>lofentanil≥cyclazocine=xorphanol>met-enkephalin> Win 44,441=hydromorphone≥butorphanol>metazocine=SKF 10047> dezocine≥ nalbuphine>morphine>fentanyl.
Such a moderate affinity makes it possible for nalorphine to antagonize the effect of other ligands or the endogenous ligand (like met-enkephalin) at δ opioid receptors while possibly acting as an agonist at other opioid receptors.
Maximal inhibitory effect of each ligand was compared to the levels of maximal inhibition by met-enkephalin, metazocine and morphine using ANOVA analysis with Dunnett's multiple comparison as post test using PRISM software (GraphPad Software, Inc.
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