Example sentences for: mesothelin

How can you use “mesothelin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mesothelin, a potential tumor serum marker, was up-regulated by Wnt-1 and down-regulated by Wnt-5a.

  • In order to examine the mechanism by which Wnt-1 or Wnt-5a regulates mesothelin or SL-1, respectively, C57mg cells were treated with either LiCl or phorbol myristic acetate (PMA).

  • We focused on two genes, mesothelin and SL-1, whose regulation by Wnts was reproducible using a variety of methods to activate the Wnt signaling pathways.

  • Whether mesothelin and SL-1 are direct targets of Wnt-1 and Wnt-5a, respectively, and whether alterations in their expression are responsible for the observed phenotypic changes in Wnt-5a/Rfz-2/C57mg cells, has yet to be determined.

  • Conversely, mesothelin appears to be up-regulated specifically by Wnt-1 and not Wnt-5a since mesothelin was not induced by co-culturing with Wnt-5a secreting cells or by activation of the chimeric Rfz-2/β 2 AR receptor (Figure 1, panels A and B).


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