Words similar to mesothelin
Example sentences for: mesothelin
How can you use “mesothelin” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the other hand, PMA treatment of C57mg cells elevated SL-1 transcript levels 6-fold but not mesothelin (Figure 2, right panel).
Mesothelin, a potential tumor serum marker, was up-regulated by Wnt-1 and down-regulated by Wnt-5a.
Whether mesothelin and SL-1 are direct targets of Wnt-1 and Wnt-5a, respectively, and whether alterations in their expression are responsible for the observed phenotypic changes in Wnt-5a/Rfz-2/C57mg cells, has yet to be determined.
Interestingly, mesothelin expression is induced in lung, ovarian, and pancreatic carcinomas where constitutive activation of Wnt signaling is caused by stabilizing mutations in beta-catenin [ 27 28 41 42 43 44 ] . The induction of mesothelin in these carcinomas may be due to misregulation of Wnt signaling as are other targets of the Wnt pathway, c-myc and cyclin D1.
Similarly, mesothelin expression was induced by Li+, an inhibitor of GSK-3β, that mimics Wnt-1.