Words similar to mesothelin

Example sentences for: mesothelin

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Whether mesothelin and SL-1 are direct targets of Wnt-1 and Wnt-5a, respectively, and whether alterations in their expression are responsible for the observed phenotypic changes in Wnt-5a/Rfz-2/C57mg cells, has yet to be determined.
The first, mesothelin, was up-regulated by Wnt-1 both by stable expression of Wnt-1 in C57mg cells and by co-culturing C57mg cells with Wnt-1 secreting cells.
The primer sequences are shown in Table 2. To determine the specificity of the primer sets to the murine mesothelin and SL-1 targets genes, we performed PCR using the primers sets with cDNA from human 293T cells, and found no amplification.
In order to examine the mechanism by which Wnt-1 or Wnt-5a regulates mesothelin or SL-1, respectively, C57mg cells were treated with either LiCl or phorbol myristic acetate (PMA).
One gene, mesothelin, exhibited a 3-fold induction in C57mg cells treated with the Wnt-1 but not the Wnt-5a secreting 293T cells (Figure 1, panel A).