Words similar to menarche
Example sentences for: menarche
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We were unable to examine the effects of other provocative exposures previously proposed by others, including exposures to light at night [ 35 ] and polycyclic aromatic hydrocarbons [ 36 ] . The observed early socioeconomic differences combined with a lack of differences in age at menarche or early body size also suggest that attention might be turned to patterns of early infection (or lack of infection) and immune response [ 37 ] .
Girls who experience a relatively early sexual maturation, typically assessed by age at menarche, tend to be more obese as adults [ 1 2 3 4 5 6 7 8 9 10 ] . For example, Garn et al [ 1 ] found that women (ages 20 to 35 y) who reported menarche before age 11 y were 2 to 3 kg/m 2heavier than those who underwent menarche after 14 y.
BMI in girls also increases with stage of sexual maturation, but relative fatness is variable, especially in girls who just attaining menarche (stage III).
The findings regarding age at menarche were confirmed in three other studies [ 2 4 9 ] and in a recent meta-analysis involving 4227 cases and 4730 controls [ 16 ] . These studies did not find that the CYP17 genotype was associated with risk of breast cancer, even when stratifying by stage of disease [ 4 9 16 ] .
In addition, we found that the inverse relation of menarcheal age to adult obesity was nonlinear, with differences in adult levels of BMI and skinfold thicknesses most evident between subjects with an early (<12 y) menarche and those who had either an intermediate or relatively late menarche.
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