Example sentences for: mechanosensitive

How can you use “mechanosensitive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a mechanosensitive scaffold that controls a large set of regulatory proteins, the actin cytoskeleton is critically poised to modulate a variety of cellular processes, including protein synthesis, cell survival, migration and proliferation [ 14 31 32 ] . One function of the cytoskeleton in gene regulation appears to be the spatial organization of transcripts and possibly their translation within the intracellular environment.

  • By looking at structures of other transport proteins, including the potassium channel [ 23], the mechanosensitive ion channel [ 24], the aquaporin water channel [ 25], and the glycerol facilitator channel [ 26], it is apparent that 7-10 TM-helices are needed to form a tunnel and transport molecules.

  • The mechanism underlying this cytoskeletal rearrangement due to shear stress is ill-defined, but it has been found to be linked to tyrosine kinase activity, levels of intracellular calcium, intact actin microfilaments, and functional microtubule network, but is independent of protein kinase C, intermediate filaments, and stretch- and shear-activated mechanosensitive K +channels [ 28].


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