Words similar to meaningful
Example sentences for: meaningful
How can you use “meaningful” in a sentence? Here are some example sentences to help you improve your vocabulary:
Chinese names of places in China itself are of course actually meaningful, although many have become distorted by Westerners.
A synthetic form of EPO, human recombinant EPO, has been successfully used to treat anemia in patients with chronic renal failure and HIV [ 1 ] . Some randomized trials (RCT) assessed the role of EPO in anemia related the cancer [ 2 3 ] . However, many of these trials were underpowered and failed to identify clinically meaningful benefits of EPO treatment.
This approach had been pioneered in the classical work of Dobzhansky and Sturtevant who used inversions in Drosophila chromosomes to construct an evolutionary tree [ 12 ] . Subsequently, mathematical methods have been developed to calculate rearrangement distances between genomes, and, using these, phylogenetic trees have been built for certain small genomes, such as plant mitochondria and herpesviruses [ 13 14 ] . These approaches, however, are applicable only to genomes that show significant conservation of global gene order, which is manifestly not the case among prokaryotes [ 15 16 17 ] . Even relatively close species such as, for example, Escherichia coli and Haemophilus influenzae, two species of the γ-subdivision of Proteobacteria, retain very little conservation of gene order beyond the operon level (typically, two-to-four genes in a row), and essentially none is detectable among evolutionarily distant bacteria and archaea [ 15 16 18 ] . Very few operons, primarily those coding for physically interacting subunits of multiprotein complexes such as certain ribosomal proteins or RNA-polymerase subunits, are conserved across a wide range of prokaryotic lineages [ 15 16 ] . On the other hand, pairwise comparisons of even distantly related prokaryotic genomes reveal considerable number of shared (predicted) operons, which creates an opportunity for a meaningful comparative analysis [ 19 ] [ 20 21 ] .
Two of the Meloidogyne genes revealed by our filters, which encode an L-threonine aldolase gene (MI01644) and a deduced protein of unknown function (MI00109), exhibit striking amino-acid identity to rhizobial proteins (48% and 51% respectively), but a complete absence of meaningful homology with any eukaryotic sequence (Table 3).
Therefore, we should choose the interpretation of presence that effectuates the Congressional purpose to provide meaningful representation to H-2A workers under their contracts.
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