Example sentences for: mdr

How can you use “mdr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In brief, our results indicate that in MCF7/ADR cells NOM can significantly sensitize their chemosensitivity to ADR, down-regulate MDR1/P-gp and GSTπ expression levels in time-dependent manner, markedly increase intracellular ADR accumulation and enhance the cell cycle blocking activity of ADR.

  • Some studies have also found that P-gp antagonists such as VRP, cyclosporin A and reserpine could induce MDR1/P-gp expression in the colon carcinoma cell line LS180-Ad50 [ 31, 32].

  • Its MDR phenotype is not altered after 3 months of serial passaging in drug-free medium [ 24, 25].

  • MRP-related MDR was not reversed by classic reversal agents of P-gp such as VRP and cyclosporin A [ 37, 38, 39].

  • It has been reported that most initially responsive patients acquire a multidrug resistance (MDR) phenotype.


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