Example sentences for: mdr

How can you use “mdr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, no change in TopoIIα gene expression level was detected in NOM-treated MCF7/ADR cells, indicating that the reversal effect of NOM on MDR in MCF7/ADR cells cannot result from modulating the gene expression of TopoIIα.

  • For MDR1, GSTπ and TopoIIα genes, after an initial denaturation at 94°C for 1.5 min, 30 cycles of PCR amplification were performed, each cycle consisting of a denaturing step of 94°C for 1.5 min, annealing at 54°C for 1 min, and extension at 72°C for 3 min, followed by a final step at 72°C for 10 min.

  • MCF7/ADR cells have been demonstrated to overexpress MDR1/P-gp, as well as the GSTπ and MRP genes.

  • From these findings it seems that NOM and other progestogen compounds show an effect of upregulated MDR1 expression in long-term treatment.

  • After treatment with 5 μM NOM, the MDR1 and GSTπ expression levels of MCF7/ADR cells were modulated in a time-dependent manner.


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