Example sentences for: mdr

How can you use “mdr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Two sets of primers were used in all reactions to yield the amplification of an endogenous control gene (β-actin, 383 bases) and the specific target genes of interest [157 bases of MDR1 (a gift from Jian Lin, Cancer Center/Institute of Cancer Research, Golumbia University, College of Physicians and Surgeons, New York, USA), 270 bases of GSTπ, 203 bases of MRP and 139 bases of TopoIIα independently (Table 1) [ 15]].

  • Some other patients show MDR even in their first treatment.

  • Previous results have shown that a daily dose of 800 mg MG resulted in a plasma concentration of 2 μM [ 21]; however, to reverse MDR, 5 μM is necessary in theory.

  • Attention has been focused recently on the study of the agents for reversing MDR.

  • ADR = adriamycin; DRO = droloxifen; GSTπ = glutathione S-transferase Pi; MDR = multidrug resistance; MG = megestrol; MRP = MDR-related protein; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2 H -tetrazolium bromide; NOM = nomegestrol; PBS = phosphate-buffered saline; P-gp = P-glycoprotein; RT-PCR = reverse transcriptase polymerase chain reaction; TAM = tamoxifen; TopoIIα = topoisomerase IIα; VRP = verapamil.


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