Example sentences for: mdm

How can you use “mdm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They first tested whether the tumours showed amplification of Mdm2.

  • mdm2 binding is dependent on the phosphorylation status of serine 20 of p53 [ 15], although phosphorylation of serines 15, 33 and 37 also play a role.

  • Over-expression of homeodomain-interacting protein kinase 2 (HIPK2), which increases p53 protein expression and/or stability, leads to a downregulation of mdm2 protein, but not mRNA [ 29 ] . Consequently, the RU486-induced increase in mdm2 mRNA expression, coupled with a decrease in that of P53, may also act in tandem to suppress the liver apoptotic capacity (Fig 1B).

  • Thus phosphorylation of the p53 protein in response to DNA damage or expression of p14Arf prevents mdm2 binding and p53 protein then accumulates in the cell.

  • Probes for mdm2, JunB, c-myc and β-actin genes were also obtained from Ambion, lnc.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast