Words similar to mdm

Example sentences for: mdm

How can you use “mdm” in a sentence? Here are some example sentences to help you improve your vocabulary:

Activation of p53 by DNA damage is also brought about by inhibition of p53-mdm2 interaction.
In the MDM of multi-spanning transmembrane α helices, isoleucine, methionine and valine are found to have relatively high mutability as hydrophobic residues, and serine and threonine also rank high in mutability as polar residues.
Over-expression of homeodomain-interacting protein kinase 2 (HIPK2), which increases p53 protein expression and/or stability, leads to a downregulation of mdm2 protein, but not mRNA [ 29 ] . Consequently, the RU486-induced increase in mdm2 mRNA expression, coupled with a decrease in that of P53, may also act in tandem to suppress the liver apoptotic capacity (Fig 1B).
In unstimulated cells, the mdm2 protein binds to the N-terminal transactivation domain of p53 and targets it for ubiquitin-dependent degradation [ 6, 7].
Hepatic RNA was extracted and quantified as we reported previously [ 10 ] . RNA was mixed with 32P-labeled c-myc, mdm2, p53, JunB, and β-actin probes, then co-precipitated, purified, and electrophoresed on 5% polyacrylamide gel.