Words similar to mdm

Example sentences for: mdm

How can you use “mdm” in a sentence? Here are some example sentences to help you improve your vocabulary:

They first tested whether the tumours showed amplification of Mdm2.
This result is mostly consistent with previous results from an MDM [ 10].
RU 486 also increased the hepatic mRNA levels of the oncogene mdm2 by 21 ± 7% (Fig 2B).
Hepatic RNA was extracted and quantified as we reported previously [ 10 ] . RNA was mixed with 32P-labeled c-myc, mdm2, p53, JunB, and β-actin probes, then co-precipitated, purified, and electrophoresed on 5% polyacrylamide gel.
In addition to the key roles in E3 ligase activity, RING finger domains have also been shown to be important for regulating subcellular localization of E3s and/or their substrates in a number of cases [ 53 54 55 56 ] . Studies have shown the MDM2 RING finger domain is required to promote nuclear export of p53 and this activity of MDM2 RING finger seems to be coupled with its ability to promote ubiquitination of p53 [ 53 54 55 ] . Rbx1/ROC1, the small RING finger subunit of the SCF E3 complexes, promotes the nuclear accumulation of Cul1, another subunit of the SCF complexes [ 56 ] . These studies have suggested a correlation between the ubiquitination activities of RING fingers and their roles in regulating subcellular localization of the E3 ligases which they are part of.