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Example sentences for: mcpromoter
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The McPromoter system consists of a generalized hidden Markov model of a promoter sequence, with six interpolated Markov chain submodels representing different segments of the promoter sequence from -250 to +50: upstream 1 and 2, TATA box, spacer, initiator and downstream.
When McPromoter was trained on the same, smaller, dataset as NNPP, the reduction in false positives was only about three- to sixfold (data not shown; for details see [ 34]).
We applied the first version of McPromoter trained on human data [ 37], which uses only sequence features and a simple Markov chain model for the whole promoter sequence.
McPromoter predictions are part of the analysis results in the Genome Annotation Database Gadfly [ 41].
Using the core promoter set to retrain the McPromoter TSS prediction tool