Words similar to mcl-
Example sentences for: mcl-
How can you use “mcl-” in a sentence? Here are some example sentences to help you improve your vocabulary:
This is consistent with the relatively high levels of apoptosis observed in these cells and their reduced survival in culture [ 29 ] . Our findings are in accord with a recent study demonstrating that Mcl-1 expression in human peripheral blood neutrophils decreases with aging [ 15 ] . As previously reported for human peripheral blood neutrophils [ 30 ] , we were unable to detect Bcl-2 in rat adherent vascular lung neutrophils, even after endotoxin treatment of animals.
These findings indicate that prolonged neutrophil survival in the lung vasculature following endotoxin administration may be mediated, at least in part, by Mcl-1.
In contrast to cells from endotoxin treated animals, adherent vascular neutrophils from control animals did not express Mcl-1 protein.
Endotoxin administration induces Mcl-1 expression in adherent vascular lung neutrophils
NF-κB, CREB and C/EBP are transcription factors known to be important in regulating the expression of various genes controlling apoptosis and inflammatory mediator production including Mcl-1, COX-2 and TNF-α [ 20 21 ] , and these were next examined.
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