Words similar to mcl-

Example sentences for: mcl-

How can you use “mcl-” in a sentence? Here are some example sentences to help you improve your vocabulary:

This is consistent with the relatively high levels of apoptosis observed in these cells and their reduced survival in culture [ 29 ] . Our findings are in accord with a recent study demonstrating that Mcl-1 expression in human peripheral blood neutrophils decreases with aging [ 15 ] . As previously reported for human peripheral blood neutrophils [ 30 ] , we were unable to detect Bcl-2 in rat adherent vascular lung neutrophils, even after endotoxin treatment of animals.
The proteins were transferred to nitrocellulose paper, and incubated at room temperature for 3 hours, or overnight, at 4°C, with mouse monoclonal anti-human Mcl-1 (1:1000), p38 MAP kinase, phosphoinositide 3 kinase (PI3K), or protein kinase B-alpha (PKB-α) (1:500) antibodies (Transduction Laboratories, San Diego, CA, USA and New England Biolabs, Inc., Beverly, MA, USA), or rabbit polyclonal anti-rat p44/42 MAP kinase (1:1000), or doubly phosphorylated anti-human Thr180/Tyr182 phospho-p38 MAP kinase (1:1000) antibodies (New England Biolabs, Inc.).
In contrast to cells from endotoxin treated animals, adherent vascular neutrophils from control animals did not express Mcl-1 protein.
These findings indicate that prolonged neutrophil survival in the lung vasculature following endotoxin administration may be mediated, at least in part, by Mcl-1.
Although expression of Mcl-1 in the neutrophils declined with time, significant amounts were still detectable 48 hours after endotoxin administration.