Example sentences for: mcl-

How can you use “mcl-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These findings indicate that prolonged neutrophil survival in the lung vasculature following endotoxin administration may be mediated, at least in part, by Mcl-1.

  • Endotoxin administration induces Mcl-1 expression in adherent vascular lung neutrophils

  • In contrast to cells from endotoxin treated animals, adherent vascular neutrophils from control animals did not express Mcl-1 protein.

  • The proteins were transferred to nitrocellulose paper, and incubated at room temperature for 3 hours, or overnight, at 4°C, with mouse monoclonal anti-human Mcl-1 (1:1000), p38 MAP kinase, phosphoinositide 3 kinase (PI3K), or protein kinase B-alpha (PKB-α) (1:500) antibodies (Transduction Laboratories, San Diego, CA, USA and New England Biolabs, Inc., Beverly, MA, USA), or rabbit polyclonal anti-rat p44/42 MAP kinase (1:1000), or doubly phosphorylated anti-human Thr180/Tyr182 phospho-p38 MAP kinase (1:1000) antibodies (New England Biolabs, Inc.).

  • Acute endotoxemia caused a marked induction of Mcl-1 in freshly isolated adherent vascular lung neutrophils, which peaked between 2 and 12 hours and remained elevated for at least 48 hours.


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