Example sentences for: mcl-

How can you use “mcl-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Treatment of rats with endotoxin resulted in a rapid induction of Mcl-1, which peaked between 2 and 12 hours.

  • Mcl-1 is an anti-apoptotic member of the Bcl-2 family whose expression is correlated with decreased apoptosis and increased survival in human neutrophils [ 15 16 ] . Western blot analysis showed that neutrophils from control animals did not express Mcl-1 protein (Fig.

  • This is consistent with the relatively high levels of apoptosis observed in these cells and their reduced survival in culture [ 29 ] . Our findings are in accord with a recent study demonstrating that Mcl-1 expression in human peripheral blood neutrophils decreases with aging [ 15 ] . As previously reported for human peripheral blood neutrophils [ 30 ] , we were unable to detect Bcl-2 in rat adherent vascular lung neutrophils, even after endotoxin treatment of animals.

  • Endotoxin administration induces Mcl-1 expression in adherent vascular lung neutrophils

  • Although expression of Mcl-1 in the neutrophils declined with time, significant amounts were still detectable 48 hours after endotoxin administration.


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