Words similar to mcf-

Example sentences for: mcf-

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Expression of the ribozyme targeted against the M6P/IGF2 receptor in MCF-7 cells resulted in down-regulation of M6P/IGF2R expression, as measured by RT-PCR, and M6P/IGF2R function, indicated by a decrease in internalization of 125I-IGF-II, and β-glucuronidase binding and endocytosis.
Our findings that ribozyme-mediated decrease in expression and functional activity of the M6P/IGF2R result in a growth advantage for MCF-7 cells indicate that this receptor acts as a negative regulator of cell growth.
Effects of M6P/IGF2R-ribozyme expression on proliferation of MCF-7 cells
The breast cancer cell lines MCF-7 and HCC1954 were obtained from American Type Culture Collection and grown under the recommended conditions.
We examined the effects of ribozyme expression on apoptosis of cultured MCF-7 cells.