Words similar to maximum-likelihood
Example sentences for: maximum-likelihood
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For all three possible unrooted tree topologies maximum-likelihood values and posterior probabilities were calculated using in-house JAVA programs that were written utilizing classes from the Phylogenetic Analysis Library version 1.0 [ 54 ] and parts of Vanilla package version 1.0 [ 54 ] . If not indicated otherwise, likelihood values were estimated using the automatically selected suitable substitution model (chosen from BLOSUM62, CPREV, Dayhoff, JTT, MTREV24, VT and WAG) with no ASRV.
The alignment of Runt domain amino acid sequences was used to construct unrooted trees by several complementary approaches (neighbour-joining, maximum-likelihood, and maximum-parsimony, described in Methods).
The neighbor-joining (Figure 3a) and maximum-likelihood trees we constructed, in combination with the fact that mammalian KCNQ1 and Anopheles KCNQ2 gene products share a striking 75% identity (despite the divergence of protostomes and deuterostomes close to 700 million years ago), suggest that gene loss in Drosophila , specifically loss of an ancestral KCNQ2 (mammalian KCNQ1 ), is the cause of this difference, rather than gene expansion in Anopheles , which may be the case for the Kv3 and Irk3 (Figure 3b) gene families.
GENEHUNTER PLUS creates maximum-likelihood haplotypes when conducting multipoint linkage analysis.
Additionally, the maximum-likelihood haplotypes for each pedigree (generated by GENEHUNTER PLUS [ S4], a modified version of GENE-HUNTER [ S5]) were examined to identify multiple recombinants.
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