Words similar to maturation
Example sentences for: maturation
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During this transition, tightly-regulated post-translational phosphorylation-dephosphorylation events and proteasome-mediated proteolytic reactions regulate the activation and inactivation of signal transduction pathways that control chromatin condensation, nuclear membrane dissolution, microtubule nucleation, and formation of a haploid oocyte [ 8 9 10 ] . Several kinases that exert major roles during OM include maturation promoting factor (MPF) [ 9 11 ] , mitogen-activated protein kinases (MAPKs) [ 12 13 ] , and the product of the c-mos protooncogene Mos kinase [ 14 15 ] . Also, during OM oocytes undergo two highly-regulated metaphase-anaphase transitions (MAT) in which homologous chromosomes are equally and randomly segregated to an oocyte and first polar body and a subsequent division in which equational division of sister chromatids results in a haploid oocyte and a second polar body.
This could occur through two different mechanisms: ( i ) Hoxc-8 actively recruits cells into the chondrocyte lineage and maintains them in the proliferating state; or ( ii ) Hoxc-8 inhibits a specific step in chondrocyte maturation.
For instance, addition of glucagon-like peptide-1, TGF-β ligands, or other factors that potentiate β-cell maturation, growth, and insulin secretion [46,47,48] may improve the methods described here.
In contrast, no reconstructed embryos developed to the blastocyst stage regardless of the maturation stage of the recipient oocytes when nocodazole-treated cells were transferred, although nuclear swelling was observed in 34.
Estrogen receptors have been identified in cultured fibroblasts of various origins and vascular smooth muscle cells [ 51 52 53 ] . Estrogens enhance proliferation of fibroblasts and inhibit vascular smooth muscle migration [ 54 55 ] . Binding of estrogens to fibroblasts also stimulates fibroblast interaction with epithelial cells with subsequent acceleration of maturation of epithelial cells [ 56 ] .
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