Words similar to markedly
Example sentences for: markedly
How can you use “markedly” in a sentence? Here are some example sentences to help you improve your vocabulary:
The protective mechanisms recommended by McKinney are opaque to the public and reflect a “business as usual” image that fails fully to account for the markedly changed circumstances and perceptions of academic biomedical research.
However, with 6 arrays per group, even a single outlier can markedly reduce the value of t even when there is no overlap between groups.
The first evidence that chemokines are associated with wound healing in vivo was reported in 1990 using the chemokine cCAF (chicken Chemotactic and Angiogenic Factor; the product of the 9E3 gene), a CXC chemokine that is now known to be the ortologue for human IL-8 [ 9 ] . cCAF is expressed to high levels very shortly after wounding and during the first 24-48 hours after injury, and remains elevated for at least 16 days after wounding [ 6 10 ] . It is primarily expressed by the fibroblasts of the granulation tissue, especially where interstitial collagen (Coll) is abundant, but the levels are also high in the endothelial cells of the microvessels, in the healing epidermis and in the connective tissue beneath the skin [ 6 11 ] . In the chicken chorioallantoic membrane (CAM) assay, low concentration of cCAF results in chemotaxis of monocyte/macrophages and lymphocytes and the formation of a granulation-like tissue beneath the chemokine-containing pellet [ 3 ] . After four days of exposure to this chemokine, the ectoderm of the CAMs becomes thickened and the amount of fibrillar collagen in the tissue is markedly increased, strongly suggesting that cCAF is able to initiate some of the primary events that lead to granulation tissue formation [ 3 ] .
Most studies have concentrated on the contribution of MMP-9 to the synovitis, because synovial fluid and serum MMP-9 levels are markedly increased in inflammatory arthropathies.
In heterozygous infants with the WT/ΔF508 genotype, sweat chloride excretion is elevated 1.5-fold over normal values compared to a tenfold increase in homozygous patients with the ΔF508/ΔF508 genotype [ 32 ] . Adult heterozygous patients have fewer problems with respiratory infections compared to homozygotes [ 5 ] . Our findings that bile acid absorption was moderately increased in heterozygotes and markedly increased in homozygotes were therefore not unexpected.
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