Example sentences for: mannose

How can you use “mannose” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Six of the eight characterized genes within the top 20 genes in this cluster encode proteins that are localized to or function in relation to the cell wall, including those involved in bud growth and cell separation ( AXL2, CIS3, SIM1 ), cell-wall proteins induced by antifungal drugs ( SVS1, PRY2, PRY4, CRH1, TOS6 ), a putative cell-wall sensor ( WSC2 ), and a Golgi mannose transporter required for glycosylation of cell-wall proteins ( VRG4 ) (see [ 21] for references).

  • FA, fatty acid; Glc, glucose; Man, mannose; 3-OMG, 3- O -methylglucose; Sorb, sorbitol

  • Seedlings grown on media containing mannose, but not 3- O -methylglucose, exhibit decreased rates of seed storage lipid breakdown.

  • The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) maps to chromosome location 6q25-27 [ 14 ] ; a chromosomal region predicted to contain a head and neck tumor suppressor gene [ 10 11 ] . It encodes for a receptor that functions in intracellular lysosomal enzyme trafficking, transforming growth factor beta activation, and IGF2 degradation (reviewed in [ 15 16 ] ). Granzyme B internalization by the M6P/IGF2R is also required for cytotoxic T cells to induce apoptosis in cells targeted for death, resulting in this receptor being referred to as a "death receptor" [ 17 ] . Elevated IGF2 levels during murine development arising from M6P/IGF2R deficiency result in cardiac abnormalities, cleft palate, fetal overgrowth and perinatal lethality [ 15 18 ] . Furthermore, large offspring syndrome frequently observed in cloned animals is associated with epigenetic changes in gene regulation and decreased M6P/IGF2R expression [ 19 ] . Thus, the M6P/IGF2R plays a crucial role in regulating mammalian fetal growth and development.

  • This led to the development of a modified enzyme, processed to expose mannose, and to its production on an industrial scale from placentas.


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