Example sentences for: mannose

How can you use “mannose” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This led to the development of a modified enzyme, processed to expose mannose, and to its production on an industrial scale from placentas.

  • The needed conceptual breakthrough was provided by the identification of a mannose receptor on macrophages and the suggestion that this might prove useful in replacement therapy for Gaucher disease [5].

  • Growth on mannose, but not 3-O-methylglucose, leads to reduced rates of seed storage lipid mobilization

  • The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) maps to chromosome location 6q25-27 [ 14 ] ; a chromosomal region predicted to contain a head and neck tumor suppressor gene [ 10 11 ] . It encodes for a receptor that functions in intracellular lysosomal enzyme trafficking, transforming growth factor beta activation, and IGF2 degradation (reviewed in [ 15 16 ] ). Granzyme B internalization by the M6P/IGF2R is also required for cytotoxic T cells to induce apoptosis in cells targeted for death, resulting in this receptor being referred to as a "death receptor" [ 17 ] . Elevated IGF2 levels during murine development arising from M6P/IGF2R deficiency result in cardiac abnormalities, cleft palate, fetal overgrowth and perinatal lethality [ 15 18 ] . Furthermore, large offspring syndrome frequently observed in cloned animals is associated with epigenetic changes in gene regulation and decreased M6P/IGF2R expression [ 19 ] . Thus, the M6P/IGF2R plays a crucial role in regulating mammalian fetal growth and development.

  • Seedlings grown on media containing mannose, but not 3- O -methylglucose, exhibit decreased rates of seed storage lipid breakdown.


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