Example sentences for: manner

How can you use “manner” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • At age 24, JQA wrote his first major work of political philosophy, in the manner of many works then, under a classical pseudonym, "Publicola."

  • We use a graph-theoretic approach to assemble the sampled side chain and main chain conformations together in a consistent and optimal manner: Each possible conformation of a residue is represented using the notion of a node in a graph.

  • A plasmid carrying a portion of the M. tuberculosis H37Rv insert in the sur3 clone was isolated in a similar manner from a Bam HI digest of sur3 genomic DNA.

  • AtCOP1 contains three conserved structural domains: a RING finger at the amino terminus, a coiled-coil domain in the middle, and a carboxyl-terminal WD40 repeat domain [ 9 10 ] . Each of the three conserved domains has been shown to mediate protein-protein interactions [ 11 12 13 ] . The subcellular localization of AtCOP1 is regulated by light in a tissue specific manner [ 14 15 ] . The hypocotyl cell nuclei contain high levels of COP1 in the dark and reduced levels in the light, suggesting that the nucleocytoplasmic partitioning of AtCOP1 is adjusted by a light-responsive mechanism [ 14 16 ] . The activity of AtCOP1 is at least in part regulated by its subcellular localization, as the degradation of HY5 is dependent upon the nuclear accumulation of AtCOP1 in the dark [ 4 ] . AtCOP1 was demonstrated to carry a single, bipartite nuclear localization signal located between the coiled-coil domain and the WD-40 domain (amino acid 294-314) and a cytoplasmic localization signal, which was mapped to a region partially overlapping with the RING finger and the coiled-coil domain (amino acid 67-117) [ 17 ] . Strikingly, AtCOP1 protein forms characteristic nuclear speckles when transiently expressed in onion epidermal cells or stably expressed in transgenic Arabidopsis [ 6 18 ] . The functional role of these speckles is currently unknown; however, a subnuclear localization signal consisting of 58 residues (amino acid 120-177) is required for their formation [ 19 ] .

  • One of the most famous dishes, mapo dofu, consists of beancurd infused with chili peppers in a manner that numbs the tongue upon impact.


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