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Example sentences for: malme-
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In response to melanoma targets mel526 and Malme-3M, which both express gp100 and MART-1 and are HLA-A*0201 positive, the two endogenous TAA-specific responses (samples from patients 132 and 461) also exhibited robust functional responses directly ex vivo (Table 1; 36.
All but two of the CTL clones elicited from endogenous anti-tumor responses (from patients 132 and 461) exhibited “efficient lysis” of both the mel526 and Malme-3M melanoma cell lines (Figure 2).
In contrast, the vaccine-elicited responses exhibited much lower reactivity to mel526 and Malme-3M (Table 1; 23.
To determine the effectiveness of tumor lysis by the different TAA-specific T cell clones that were propagated, clones were analyzed for their ability to lyse melanoma cell lines mel526 and Malme-3M.
While Malme-3M and mel526 express both MART and gp100, A375 does not express MART or gp100 and served as a negative control.