Words similar to main-chain

Example sentences for: main-chain

How can you use “main-chain” in a sentence? Here are some example sentences to help you improve your vocabulary:

This bias normally influences both the orientation and conformation of the ligand in the active site, which usually represents a local minimum conformation [ 14 ] . More importantly, the lock and key concepts used to evaluate enzyme-substrate binding, in reality, refer to flexible locks and keys that are both in constant dynamic (thermal) motion [ 15 ] . For example, an analysis of conformational changes upon complex formation for a representative set of 39 pairs of ligand-free and ligand-bound structures showed that 50% of these proteins undergo substantial main-chain and side chain conformational changes when the ligand is bound [ 15 ] .
Most of these positions are partially shielded from solvent and/or contribute main-chain hydrogen-bonding interactions.