Words similar to lumican

Example sentences for: lumican

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Among the genes most highly correlated with IL-8 in tumor tissues are KLF2, PS1, VEGF, and tumor necrosis factor receptor-1 (TNFR-1), lumican (keratin sulfate proteoglycan), claudin-3, and perlecan.
Lumican expression has previously been correlated with higher tumor grade, lower estrogen levels in the tumor and younger age of patients in human breast cancer [ 21 ] . In addition, lumican is structurally related to both biglycan which is among the top IL-8-tumor related genes and the human embryonal carcinoma marker antigen TRA-1-60 [ 22 ] . These relationships support the hypothesis that lumican may be a tumor related protein involved with IL-8's tumorigenic function.
Along with lumican, claudin-3, KLF2, PS1, VEGF and TNFR-1 mentioned above, these include several secreted proteins (secreted apoptosis related protein 1 and NPDC1) which are also likely to function in coordination with IL-8; several genes from the well-known family of complement factors (C1 esterase, human complement C4A and complement factor B); and several unknown or hypothetical genes.