Words similar to lumican

Example sentences for: lumican

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Among the genes most highly correlated with IL-8 in tumor tissues are KLF2, PS1, VEGF, and tumor necrosis factor receptor-1 (TNFR-1), lumican (keratin sulfate proteoglycan), claudin-3, and perlecan.
Along with lumican, claudin-3, KLF2, PS1, VEGF and TNFR-1 mentioned above, these include several secreted proteins (secreted apoptosis related protein 1 and NPDC1) which are also likely to function in coordination with IL-8; several genes from the well-known family of complement factors (C1 esterase, human complement C4A and complement factor B); and several unknown or hypothetical genes.
Lumican expression has previously been correlated with higher tumor grade, lower estrogen levels in the tumor and younger age of patients in human breast cancer [ 21 ] . In addition, lumican is structurally related to both biglycan which is among the top IL-8-tumor related genes and the human embryonal carcinoma marker antigen TRA-1-60 [ 22 ] . These relationships support the hypothesis that lumican may be a tumor related protein involved with IL-8's tumorigenic function.