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Example sentences for: luca

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An alternative scenario holds that the RDRPs are ancient enzymes that diverged from the evolutionary precursor of DDRP at a very early, pre-LUCA stage of evolution, albeit after the duplication that led to the differentiation of the β and β' versions of the DPBB domain.
The above analysis shows that LUCA probably encoded three distinct DPBB domains.
Eukaryotes have maintained their introns because they confer the capacity to create evolutionary novelty through exon shuffling [ 2 ] . The introns-early theory predicts that at least some of the extant eukaryotic introns are direct descendants of the primordial sequences in the LUCA [ 2 3 4 5 ] . The alternate view, "introns-late", suggests that the last common ancestor was intron-free and that spliceosomal introns have originated in eukaryotes from recent invasions by autocatalytic RNAs (e.g.
Analysis of the conserved protein superfamilies within these folds and their phyletic distribution patterns suggests that diverse versions of these domains with distinct functions were already present in LUCA.
Although the major events in the evolution of polymerases occurred at very early stages of evolution and LUCA already had an advanced DDRP resembling the extant forms, subsequent lineage-specific elaborations of considerable magnitude have occurred.