Words similar to loxp

Example sentences for: loxp

How can you use “loxp” in a sentence? Here are some example sentences to help you improve your vocabulary:

The loxP flanked neo cassette, and trimer of the SV40 polyadenylation sequence (tpA), were from plasmid PGKneotpAlox2 [ 4].
Cre-mediated targeting of single copy transgenes to specific genomic sites that have previously been marked by loxP elements has also been described both in somatic cells and more recently in ES cells using a double LoxP targeting strategy [ 22, 23].
A MCS containing the restriction sites for XhoI, ApaI, SacII, NotI, SacI, EcoRV, and KpnI was synthesized and inserted downstream of the second loxP site by digesting the DNA with XhoI and KpnI and ligating in the MCS, which had been synthesized to have compatible cohesive ends.
More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.
The pgk promoter was flanked by loxP elements so that it could be deleted by the action of Cre recombinase.