Words similar to loxp

Example sentences for: loxp

How can you use “loxp” in a sentence? Here are some example sentences to help you improve your vocabulary:

Importantly the neo gene is flanked by loxP sequences permitting loss of G418 resistance where useful.
The Cre- loxP site specific recombination system [ 1] is widely used for production of tissue-specific and conditional knockout alleles in mice [ 2, 3].
More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.
Cre-mediated targeting of single copy transgenes to specific genomic sites that have previously been marked by loxP elements has also been described both in somatic cells and more recently in ES cells using a double LoxP targeting strategy [ 22, 23].
The loxP flanked neo cassette, and trimer of the SV40 polyadenylation sequence (tpA), were from plasmid PGKneotpAlox2 [ 4].