Example sentences for: loxp

How can you use “loxp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cre-mediated targeting of single copy transgenes to specific genomic sites that have previously been marked by loxP elements has also been described both in somatic cells and more recently in ES cells using a double LoxP targeting strategy [ 22, 23].

  • Recombination between loxP elements in ES cells was mediated by introducing a Cre expression plasmid, pHDMCCre8 (provided by Dr. Klaus Kaestner).

  • The 3' arm of homology contains nucleotides 29 to 626 of the Neo coding sequence with an accompanying pgk promoter flanked by loxP elements.

  • The Cre- loxP site specific recombination system [ 1] is widely used for production of tissue-specific and conditional knockout alleles in mice [ 2, 3].

  • Importantly the neo gene is flanked by loxP sequences permitting loss of G418 resistance where useful.


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