Words similar to lowering
Example sentences for: lowering
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This variability reflects our strategy to document highly dynamic, complex, novel and otherwise notable patterns extensively, while progressively lowering the number of images documenting common or simple expression patterns.
Intestinal calcium absorption is increased after feeding a low calcium diet or under conditions of increased calcium needs, such as during growth, via a parathyroid hormone (PTH)-vitamin D mediated process [ 3 ] . A lowering of serum calcium levels stimulates the secretion of PTH that then activates the renal conversion of inactive 25-hydroxyvitamin D to the active hormonal metabolite 1,25-dihydroxyvitamin D. At the intestine, 1,25-dihydroxyvitamin D, acting through a nuclear receptor, stimulates transcription of vitamin D-mediated genes, including calbindin D, involved in calcium transport thereby acting as the primary hormonal regulator of active intestinal calcium transport [ 3 ] . It is thus likely that any putative key molecular player in calcium absorption, such as CaT1 or ECaC1, should be a prime target for hormonal regulation by 1,25-dihydroxyvitamin D. However, to date, neither CaT1 nor ECaC1 expression has been shown to be related to serum 1,25-dihydroxyvitamin D or vitamin D status [ 10 16 ] .
P2X 2 receptors were expressed in Xenopus oocytes by mRNA injection [ 35 ] . In order to obtain outside-out patches with a single channel from Xenopus oocytes, we decreased expression by reducing the amount of mRNA from 50 ng to 25 ng, lowering the incubation temperature from 17 to 14°C, and shortening the incubation time to 16 hours.
The lowering of duties and trade barriers at a time of considerable shipping expansion had the desired effect, and Santa Cruz de Tenerife and Las Palmas soon became two of the world’s busiest ports.
Inaccurate estimates of CHD risk could lead to prescription of lipid lowering drugs to patients in whom their net benefit has not been established.