Example sentences for: lowering

How can you use “lowering” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This variability reflects our strategy to document highly dynamic, complex, novel and otherwise notable patterns extensively, while progressively lowering the number of images documenting common or simple expression patterns.

  • Intestinal calcium absorption is increased after feeding a low calcium diet or under conditions of increased calcium needs, such as during growth, via a parathyroid hormone (PTH)-vitamin D mediated process [ 3 ] . A lowering of serum calcium levels stimulates the secretion of PTH that then activates the renal conversion of inactive 25-hydroxyvitamin D to the active hormonal metabolite 1,25-dihydroxyvitamin D. At the intestine, 1,25-dihydroxyvitamin D, acting through a nuclear receptor, stimulates transcription of vitamin D-mediated genes, including calbindin D, involved in calcium transport thereby acting as the primary hormonal regulator of active intestinal calcium transport [ 3 ] . It is thus likely that any putative key molecular player in calcium absorption, such as CaT1 or ECaC1, should be a prime target for hormonal regulation by 1,25-dihydroxyvitamin D. However, to date, neither CaT1 nor ECaC1 expression has been shown to be related to serum 1,25-dihydroxyvitamin D or vitamin D status [ 10 16 ] .

  • P2X 2 receptors were expressed in Xenopus oocytes by mRNA injection [ 35 ] . In order to obtain outside-out patches with a single channel from Xenopus oocytes, we decreased expression by reducing the amount of mRNA from 50 ng to 25 ng, lowering the incubation temperature from 17 to 14°C, and shortening the incubation time to 16 hours.

  • The lowering of duties and trade barriers at a time of considerable shipping expansion had the desired effect, and Santa Cruz de Tenerife and Las Palmas soon became two of the world’s busiest ports.

  • Inaccurate estimates of CHD risk could lead to prescription of lipid lowering drugs to patients in whom their net benefit has not been established.


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