Words similar to loss-of-function

Example sentences for: loss-of-function

How can you use “loss-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

Most genetic screens for life-span regulators in Drosophila and other organisms, such as C. elegans , have involved loss-of-function mutations and therefore have identified negative regulators of life span [ 14, 15, 42, 43].
They also showed that only about 40% of the genes had similar loss-of-function phenotypes in both cell lines.
Genetic alterations such as amplification, deletion, translocation and rearrangement could result in either gain-of-function or loss-of-function mutations in genes that modulate aspects of cell proliferation, differentiation, motility and survival.
In theory, tab mutants could act downstream of or parallel to CDC15, and could be either loss-of-function mutations in genes that inhibit exit from mitosis or gain-of-function mutations in genes that promote exit from mitosis.
We found that E2F loss-of-function mutations were the strongest modifiers as they completely suppressed the phenotype.