Words similar to longstanding
Example sentences for: longstanding
How can you use “longstanding” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is intriguing that CD36 expression was not detected in PTECs in diabetic mice with longstanding hyperglycemia in vivo, although underlying mechanisms for the species-dependent differential regulation of CD36 in PTECs in vivo and in vitro between mouse and human remain unclear at this time.
One would also have to forgive the Indian subcontinent's most highly trained cardiologist for failing to recognize that It's me dickey ticker, doctor--which sounds as if the patient requires the services of a watch-repairer--is an allusion to longstanding heart disease.
Moreover, it is possible that β-cells from patients with longstanding diabetes have a higher threshold for an apoptotic response to DNA-damage than β-cells in normal subjects, as it has been shown that this threshold increases with age [ 43 ] . Consequently, β-cells with high levels of DNA damage from younger individuals with a shorter duration of diabetes might be eliminated by apoptosis, while similarly damaged β-cells from older individuals, who are likely to have had diabetes for a longer time may be resistant to apoptosis and so remain.
As noted by Doherty and Zinkernagel [ 4 ] , simple dominance for resistance to each of several diseases can create allele-specific overdominance for total fitness, if different alleles confer resistance to different diseases [ 10 31 ] . For these reasons, our results, while relevant to the longstanding debate over the relative importance of various kinds of balancing selection in maintaining MHC diversity [ 32 ] , raise doubts about only one of several lines of evidence for the overdominance hypothesis.
DiGenova has longstanding relationships with reporters, dating from his days as U.S. attorney for the District of Columbia.
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