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Example sentences for: loh

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High-molecular weight DNA from frozen tumor and the corresponding peripheral blood specimens was isolated as previously described [ 14 ] . A panel of 49 sequence tagged repeat polymorphic (STRP) (24 markers mapped to chromosome 2q, nine on 5p, 11 on 6p, and five on 11q) markers, previously analyzed for LOH, was chosen for scoring MSI [ 14 15 16 17 ] . The criterion for analysis and classification of MSI has been described earlier [ 51 52 ] .
These results were analyzed in conjunction with other LOH data available for markers on 3p, 11p, 13q, 16p, 17p, and 17q in an effort to place chromosome 18p alterations on the breast cancer progression pathway.
3 also were affected by LOH and exhibited loss of expression in teratoma [ 9 ] . The BTG1 , APAF1 , and NEDD1 genes mapped to the 12q22 common-deletion region, and thus considered as candidate TSGs in GCT [ 8 10 11 ] .
3 LOH in the DCIS component could also be found in the invasive component isolated for analysis (Fig.
To further characterize the 5p region in CC, we performed a high-resolution deletion mapping in invasive cancer and found that 60% of patients exhibit LOH.