Example sentences for: locf

How can you use “locf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The LOCF assumes (unrealistically) that the missing data after patient's withdrawal are the same as the last value observed for that patient.

  • BP = blood pressure; HCTZ = hydrochlorothiazide; DBP = diastolic blood pressure; ITT = intent to treat; MCAR = missing completely at random; ICH = International Conference on Harmonization; LOCF last-observation-carried-forward; PMI = proper multiple imputation; MAR = missing at random; PI = partial imputation.

  • Another imputation method, which is in-between the LOCF and PMI, is the partial imputation (PI) or improved LOCF method [ 15 ] . The idea of this method is quite simple.

  • LOCF is popular among practitioners because it is simple to put into effect and because of a misconception that it is conservative (meaning working against an effective treatment group).

  • Since PI does less imputation, it is less biased than LOCF because the assumption of stability usually does not hold.


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