Words similar to locf
Example sentences for: locf
How can you use “locf” in a sentence? Here are some example sentences to help you improve your vocabulary:
BP = blood pressure; HCTZ = hydrochlorothiazide; DBP = diastolic blood pressure; ITT = intent to treat; MCAR = missing completely at random; ICH = International Conference on Harmonization; LOCF last-observation-carried-forward; PMI = proper multiple imputation; MAR = missing at random; PI = partial imputation.
Some simulation results under various missing data processes demonstrated the potential usefulness of PI over the methods of using all available data and LOCF [ 15 ] . However, more experience is still needed to test this new method in practice.
Since LOCF requires the strong assumption of stability, the more it imputes the more bias it introduces if the assumption of stability does not hold.
Another imputation method, which is in-between the LOCF and PMI, is the partial imputation (PI) or improved LOCF method [ 15 ] . The idea of this method is quite simple.
The LOCF assumes (unrealistically) that the missing data after patient's withdrawal are the same as the last value observed for that patient.