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Example sentences for: lncap

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LNCaP-FGC cells were obtained from ATCC (order number CRL-10995) and maintained in RPMI supplemented with 10% FBS as described [ 46 ] . We noticed that LNCaP cells at low density grow best on 15 cm Falcon 3025 tissue culture dishes and that the effects of SKP2 overexpression were most pronounced when cells were cultured on these dishes (data not shown).
In three of these cell lines, LNCaP, MDA PCa 2a and MDA PCa 2b, mutations in the ligand-binding domain of the AR confer broad steroid-binding affinity [ 8, 9].
Responses to androgen of the set of transcripts identified as androgen-responsive in the LNCaP experiments were examined in each of these cell lines.
In the first, LNCaP cells were treated for 24 hours with dihydrotestosterone (DHT), the predominant androgen found in the prostate in vivo.
For example, IL-6 acting via its receptor has been shown to activate STAT3 in LNCaP cells.