Example sentences for: lmna

How can you use “lmna” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The exact mechanism by which LMNA mutations cause disease is not clearly elucidated at this time.

  • However, the mechanism by which LMNA mutations lead to cardiac versus skeletal muscle disease is unknown.

  • Subjects with LMNA mutations should be carefully evaluated for both pacemakers and defibrillators.

  • Of note, mice with a null allele in lmna display a phenotype only in the homozygous state [ 22 ] . The mutation we now describe is predicted to generate a substantial protein fragment consisting of the first 37 KDa of lamin A/C.

  • Currently, there are at least two theories regarding the effects of LMNA [ 24 ] . The first postulates that disruptions of the inner nuclear membrane affect heterochromatin scaffolding and thereby gene expression.


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