Example sentences for: lmna

How can you use “lmna” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Of note, mice with a null allele in lmna display a phenotype only in the homozygous state [ 22 ] . The mutation we now describe is predicted to generate a substantial protein fragment consisting of the first 37 KDa of lamin A/C.

  • However, it is clear that mutations in LMNA cause tissue-specific disease affecting various differentiated cells including cardiac and skeletal muscle, adipocytes and neurons.

  • PCR primers were designed to amplify all twelve protein coding exons of LMNA (Table I).

  • Currently, there are at least two theories regarding the effects of LMNA [ 24 ] . The first postulates that disruptions of the inner nuclear membrane affect heterochromatin scaffolding and thereby gene expression.

  • All twelve exons of LMNA were screened by denaturing high performance liquid chromatography (DHPLC) and single strand conformation polymorphism (SSCP) (Figure 4).


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