Words similar to lipid-lowering
Example sentences for: lipid-lowering
How can you use “lipid-lowering” in a sentence? Here are some example sentences to help you improve your vocabulary:
Likewise, in a population-based study from the Netherlands, merely 16% of individuals eligible for lipid-lowering drugs were actually treated [7].
For each scenario, we first asked subjects to estimate the 5-year risk of CHD events without any therapy, then to estimate the 5-year risk if the patient were taking a lipid-lowering agent.
Their estimates of the relative risk reduction associated with therapy using lipid-lowering drugs were more accurate, but their estimates of the absolute risk reductions were also inaccurate because of their overestimation of baseline CHD risk.
Friedmann et al used a mail survey to measure 599 physicians' estimates of risk for three CHD risk scenarios, one of which involved lipid-lowering therapy.
Even if these findings are not confirmed after further study, one could still make a compelling argument that lipid-lowering therapy (barring contraindications) should be initiated early and universally in patients who present with an acute coronary syndrome: First, the long-term safety and effectiveness of statins for the secondary prevention of stable coronary disease is well-established [ 1 2 3 ] ; Second, as evidenced by MIRACL, these agents are safe when initiated at the time of hospitalization for an acute coronary syndrome; Third, the in-hospital initiation of lipid-lowering therapy appears to promote greater long-term utilization of these agents [ 18 19 20 21 ] . Finally, although lipid levels may be unreliable in the setting of an acute coronary syndrome (excepting total :HDL and LDL:HDL cholesterol ratios [ 22 ] ) the overwhelming majority of patients with coronary disease will ultimately require both pharmacologic and non-pharmacologic lipid-lowering interventions to attain recommended cholesterol targets [ 23 24 25 ] ; newer guidelines are even more stringent [ 26 ] . Furthermore, data from the recently presented Heart Protection Study suggest that clinical benefits may accrue independent of baseline cholesterol level [ 4 ] . Thus, to withhold lipid-lowering therapy from patients who present with an acute coronary syndrome would be to accept the status quo, and to date our efforts at cholesterol lowering in the secondary prevention setting have been dismal [ 27 28 ] .
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