Words similar to linkage
Example sentences for: linkage
How can you use “linkage” in a sentence? Here are some example sentences to help you improve your vocabulary:
Furthermore, extremely dense SNP maps have the potential to make possible genome-wide association studies for complex traits that bypass shortcomings of current genetic linkage analyses [ 3 4 ] .
Non-replication of linkage results in complex diseases is common, and may be due to the low power of studies to detect genes of relatively small effect and/or to a high degree of genetic heterogeneity among families.
All characterized members of this family are peptidases, and they either hydrolyze the D-γ-glutamyl-meso-diaminopimelate linkage or N -acetylmuramate- L-alanine linkage [ 19, 25].
We chose E. coli K12 as the target genome for functional linkage detection and the other genomes as reference genomes for constructing the gene cluster phylogenetic profiles.
Further, this implies that putative Ch6p alleles associated with CVID or IgGSD susceptibility occur on many HLA haplotypes that are common in Caucasians in central Alabama [ 10 ] and in Caucasians from a large national bone marrow donor program [ 14 ] . The present observations also confirm and extend the reports of association of HLA haplotype A*01-B*08 (or an extended haplotype containing A*01 and B*08) with heritable forms of immunoglobulin deficiency demonstrated in family-based analyses [ 3 6 19 20 21 22 ] . It is likely that a candidate gene(s) for CVID or IgGSD exists in the HLA class II region, [ 6 19 20 21 22 23 ] . Because the class II region is closer to the HLA-B locus than to the HLA-A locus, it is plausible that candidate gene(s) for CVID or IgGSD in the class II region are in greater linkage disequilibrium with HLA-B than HLA-A.
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